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Review Questions

  1. What are the two major phases of the cell division cycle, and what are the events that occur in those stages?

  2. Why are yeasts so useful for the analysis of fundamental cellular processes like cell division?

  3. Where does the cell cycle arrest if chromosomes are not aligned properly on the mitotic spindle?

  4. Why does the activity of cyclin-dependent kinases oscillate in the cell cycle?

  5. How do cyclin-dependent kinases trigger cell cycle events?

  6. How does the ubiquitination of a protein lead to its destruction?

  7. How does the anaphase-promoting complex initiate anaphase?